Cancer Biology

Hallmarks of cancer writing assignment.

The Hallmarks of Cancer is a landmark review article. The authors found and cited other studies and put it together in an article known as a review article. Read the Hallmarks of Cancer posted on Cougar courses. For this assignment you will also need to use and site a primary source/article. A primary peer-reviewed article is not a review article; it contains original research that has not been previously published. In order to find primary peer-reviewed articles you will need to use pubmed.gov or google scholar. Wiki-anything is not primary sources. In the Hallmarks of Cancer you will notice when they cite someone else’s work they end the sentence (Last name, Year of publication). Please do the same in this writing assignment and in your Cancer Brochure assignment. This writing assignment will provide some foundational information that you will be able to utilize in your cancer brochure.

1. List the specific hallmarks of cancer discussed in the review article, ranking them in order of which you think should be the focus of more investigation in an effort to develop more therapeutic options for patients.

2. Select one of the hallmarks of cancer and describe in detail what occurs in that hallmark towards carcinogenesis. Make sure to mention genes and mutations that contribute to that process. I highly recommend, (if possible) you make an effort to find a gene and mutation that occurs in the cancer for your Cancer Brochure assignment. Identify a gene and mutation that is involved in the carcinogenesis hallmark that is NOT mentioned in the review article. If the specific cancer mutation you found for your cancer is not mentioned in the review article you do not need to find a new one. If the specific cancer mutation and the hallmark mutation are in the same gene/mutation find an additional gene and/or mutation. How prevalent is that mutation in your cancer of interest? Is it a specific mutation in the gene that leads to its effect or does the cancer alter the gene with a plethora of different mutations in different patients? Now that you know a lot more about this hallmark and your cancer, search and find if there are therapeutics for your hallmark. What is the therapeutic? Is it a specific therapeutic for the hallmark that can be used for multiple cancers? Or is it specifically used to treat your cancer of interest and not specifically the hallmark? How do patients receive that therapy?

3. Do you think there is a “silver bullet” cancer therapeutic that has yet to be discovered? By silver bullet I mean a cure that would work for all cancers. Please provide an explanation for your answer.

When you are citing someone else’s work paraphrase do not quote and cite at the end of the sentence (last name of last author and year it was published).

At the end of your assignment please list the references/sources you used.

Do not exceed 3 pages double spaced, Arial font 11 or 12. Not including your reference that can be on another page and does not have to be double spaced.

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Healing And Autonomy

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Online Discussion

Online Discussion assignments for this course will consist of multiple  questions/topics presented via a forum created for each module. You  must create a post of at least 200-words in answer to ONE of the week’s  Discussion questions/topics. Be sure to identify the title of the question when posting.

  1. Galaxy stuff:   In the chapters on stars, we learned why we are “star stuff.” Explain  why we are also “galaxy stuff.” Does the fact that the entire galaxy  was involved in bringing forth life on Earth change your perspective on  Earth or on life? If so, how. If not, why not?
  2. Galactic Ecosystem:  We have likened the star-gas-star cycle in our Milky Way to the  ecosystem that sustains life on Earth. Here on our planet, water  molecules cycle from the sea to the sky to the ground and back to the  sea. Our bodies convert atmospheric oxygen molecules into carbon  dioxide, and plants convert carbon dioxide back into oxygen molecules.  How are the cycles of matter on Earth similar to the cycles of matter in  the galaxy? How do they differ? Do you think the term ecosystem is  appropriate in discussions of the galaxy?

Health Project

2-3 pages essay of the topic from the module

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Neurological Symptoms

Case Study 1 Headaches: Neurological system and continue practicing documentation of a focused/episodic SOAP note for Assignment 

A 20-year-old male complains of experiencing intermittent headaches. The headaches diffuse all over the head, but the greatest intensity and pressure occurs above the eyes and spreads through the nose, cheekbones, and jaw.

 

Episodic/Focused SOAP Note Template

Patient Information:

Initials, Age, Sex, Race

S.

CC (chief complaint) a BRIEF statement identifying why the patient is here – in the patient’s own words – for instance, “headache”, NOT “bad headache for 3 days”.

HPI: This is the symptom analysis section of your note. Thorough documentation in this section is essential for patient care, coding, and billing analysis. Paint a picture of what is wrong with the patient. Use LOCATES Mnemonic to complete your HPI. You need to start EVERY HPI with age, race, and gender (e.g., 34-year-old AA male). You must include the seven attributes of each principal symptom in paragraph form, not a list. If the CC was “headache”, the LOCATES for the HPI might look like the following example:

Location: head

Onset: 3 days ago

Character: pounding, pressure around the eyes and temples

Associated signs and symptoms: nausea, vomiting, photophobia, phonophobia

Timing: after being on the computer all day at work

Exacerbating/ relieving factors: light bothers eyes, Aleve makes it tolerable but not completely better

Severity: 7/10 pain scale

Current Medications: include dosage, frequency, length of time used and reason for use; also include OTC or homeopathic products.

Allergies: include medication, food, and environmental allergies separately (a description of what the allergy is ie angioedema, anaphylaxis, etc. This will help determine a true reaction vs intolerance).

PMHx: include immunization status (note date of last tetanus for all adults), past major illnesses and surgeries. Depending on the CC, more info is sometimes needed
Soc Hx: include occupation and major hobbies, family status, tobacco & alcohol use (previous and current use), any other pertinent data. Always add some health promo question here – such as whether they use seat belts all the time or whether they have working smoke detectors in the house, living environment, text/cell phone use while driving, and support system.

Fam Hx: illnesses with possible genetic predisposition, contagious or chronic illnesses. The reason for the death of any deceased first degree relatives should be included. Include parents, grandparents, siblings, and children. Include grandchildren if pertinent.

ROS: cover all body systems that may help you include or rule out a differential diagnosis You should list each system as follows: General: HeadEENT: etc. You should list these in bullet format and document the systems in order from head to toe.

Example of Complete ROS:

GENERAL:  No weight loss, fever, chills, weakness or fatigue.

HEENT:  Eyes:  No visual loss, blurred vision, double vision or yellow sclerae. Ears, Nose, Throat:  No hearing loss, sneezing, congestion, runny nose or sore throat.

SKIN:  No rash or itching.

CARDIOVASCULAR:  No chest pain, chest pressure or chest discomfort. No palpitations or edema.

RESPIRATORY:  No shortness of breath, cough or sputum.

GASTROINTESTINAL:  No anorexia, nausea, vomiting or diarrhea. No abdominal pain or blood.

GENITOURINARY:  Burning on urination. Pregnancy. Last menstrual period, MM/DD/YYYY.

NEUROLOGICAL:  No headache, dizziness, syncope, paralysis, ataxia, numbness or tingling in the extremities. No change in bowel or bladder control.

MUSCULOSKELETAL:  No muscle, back pain, joint pain or stiffness.

HEMATOLOGIC:  No anemia, bleeding or bruising.

LYMPHATICS:  No enlarged nodes. No history of splenectomy.

PSYCHIATRIC:  No history of depression or anxiety.

ENDOCRINOLOGIC:  No reports of sweating, cold or heat intolerance. No polyuria or polydipsia.

ALLERGIES:  No history of asthma, hives, eczema or rhinitis.

O.

Physical exam: From head-to-toe, include what you see, hear, and feel when doing your physical exam. You only need to examine the systems that are pertinent to the CC, HPI, and History. Do not use “WNL” or “normal.” You must describe what you see. Always document in head to toe format i.e. General: Head: EENT: etc.

Diagnostic results: Include any labs, x-rays, or other diagnostics that are needed to develop the differential diagnoses (support with evidenced and guidelines)

A.

Differential Diagnoses (list a minimum of 3 differential diagnoses).Your primary or presumptive diagnosis should be at the top of the list. For each diagnosis, provide supportive documentation with evidence-based guidelines.

APA citation 4 to 5 Reference with 5 years.

For The Grade

The eText, page 255, cites research that suggests religious motivation for joining militant groups may be overrated. After reading the section regarding Jihadi Salafists present an argument that may challenge the research or offer your own reasons for supporting the research findings.  250 words.

Essay

Read the case study of the textbook and answer the questions below; include justification of your answers.

1.  Based on what is known about the test results in this case and the hypothetical test in the first case, do you think the out come in each case was fair?  Be sure you address each one separately and justify your answers.

2. Would you recommend that the testing of female athletes be continued to ensure that male athletes do not compete as females?  Or should all such testing be banned?

3.  Watch the video below and then indicate if your answer to question 2 changes or stays the same.  Explain why or why not.

Transgender Track Athlete Wins CT State Championship, Debate Ensues (Links to an external site.)

4.  The video below presents another case: Explain how this situation is different and how you think the laws could be changed to address this particular situation.

Transgender boy wins girls' wrestling title (Links to an external site.)

I attract the case study

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Materials And Procedure

Follow the instructions..

Independent Variable: Gender

Dependent Variable: Their behavior was acceptable and Their behavior was immoral.

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Research health

Research health care legislation that is being considered in your state. What impact might this legislation have on your future practice? What impact does it have on the collective practice of nurses in your state? How do you envision yourself potentially becoming involved in political advocacy for the profession in your future practice?